Dynamic functional connectivity analysis reveals transient states of dysconnectivity in schizophrenia
نویسندگان
چکیده
منابع مشابه
Dynamic functional connectivity analysis reveals transient states of dysconnectivity in schizophrenia
Schizophrenia is a psychotic disorder characterized by functional dysconnectivity or abnormal integration between distant brain regions. Recent functional imaging studies have implicated large-scale thalamo-cortical connectivity as being disrupted in patients. However, observed connectivity differences in schizophrenia have been inconsistent between studies, with reports of hyperconnectivity an...
متن کاملThalamocortical dysconnectivity in schizophrenia.
OBJECTIVE The thalamus and cerebral cortex are connected via topographically organized, reciprocal connections. Previous studies have revealed thalamic abnormalities in schizophrenia; however, it is not known whether thalamocortical networks are differentially affected in the disorder. To explore this possibility, the authors examined functional connectivity in intrinsic low-frequency blood-oxy...
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Introduction Studying functional connectivity (correlations among voxels) among brain networks helps reveal important information about brain function in healthy and diseased brain. Being a major psychotic disorder, schizophrenia, is known to disrupt cognitive and motor functions and it has been shown to disrupt task-related functional networks during performance of certain tasks. Functional ne...
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Resting-state fMRI (RS-fMRI) has become a useful tool to investigate the connectivity structure of mental health disorders. In the case of major depressive disorder (MDD), recent studies regarding the RS-fMRI have found abnormal connectivity in several regions of the brain, particularly in the default mode network (DMN). Thus, the relevance of the DMN to self-referential thoughts and rumination...
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The first functional neuroimaging studies of schizophrenia, using single photon (SPET) and positron emission tomography (PET), led to the notion of abnormal 'hypofrontality' (Ingvar & Franzen, 1974). Although consistent with data linking schizophrenia with deficits in frontal function, the popularity of'hypofrontality' gradually faded as technically and methodologically more sophisticated studi...
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ژورنال
عنوان ژورنال: NeuroImage: Clinical
سال: 2014
ISSN: 2213-1582
DOI: 10.1016/j.nicl.2014.07.003